Gamma scintigraphy is a non-invasive imaging technique that uses a safe radioactive marker to track the movement and release of oral drug formulations inside the body.

Scientific Benefits

Tracks Transit and Disintegration: By tagging the oral product (such as a tablet or capsule) with a gamma-emitting tracer, scientists can visualize how the product moves through the gastrointestinal (GI) tract and where it disintegrates

Monitors Drug Release: Gamma scintigraphy can show when and where the drug is released from its formulation, helping researchers understand the timing and location of drug availability in the GI tract.

Quantifies Gastric Emptying and GI Transit: The technique provides quantitative data on how long the product stays in the stomach and how quickly it moves through the intestines, which is important for optimizing drug absorption.

Compares Formulations: Scientists can directly compare different oral formulations (e.g., immediate-release vs. controlled-release) to see which delivers the drug most effectively to the desired site.

Supports Regulatory Submissions: The clear, quantitative data help demonstrate how the product behaves in the body, supporting claims and regulatory approval.

In Summary: Gamma scintigraphy gives oral formulation scientists detailed, quantitative information on how oral products travel and release drugs in the body, helping to optimize formulations and support regulatory approval.